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Peripheral artery disease: when leg pain is a circulation warning

Cramping legs when you walk are easy to brush off as “just getting older.” Often they’re a sign that narrowed arteries are starving your legs of blood, and a warning about your heart health too. Here’s what PAD is, why it matters, and how it’s treated.

1 in 20

adults over 50 have PAD, and many don’t know it

Minutes

to detect with a simple, painless ABI test

An older woman rubbing her aching lower leg and ankle

What is peripheral artery disease?

Peripheral artery disease, or PAD, is a common circulation problem in which the arteries that carry blood to your legs and feet become narrowed by plaque. With less blood getting through, the muscles don't get the oxygen they need, especially when you're active.

It's caused by atherosclerosis: the same process that narrows the arteries of the heart.

Often felt while walking

The first clue is usually leg cramping that comes on with activity and fades with rest.

A whole-body signal

PAD points to artery disease elsewhere, so treating it protects your heart and brain too.

Manageable, not hopeless

It can't be fully reversed, but blood flow can be restored and the disease slowed.

Dr. Rex C. Manayan

Dr. Rex C. Manayan

Board-Certified • Fellowship-Trained Vascular Surgeon

What our doctors think of PAD

“The patients who do best with PAD are the ones we meet early. A five-minute ankle-brachial test tells us exactly where things stand, and from there almost everything we do is a small puncture, not an operation.”

Signs & symptoms

PAD can be quiet for years. When it does show up, there are three ways to catch it: by how your legs feel, what you see, and the patterns you notice.

What you Feel

A woman seated on a couch, gripping her aching calf with both hands
Cramping or aching in the calves, thighs, or hips when you walk, easing within minutes of resting
Numbness, tingling, or weakness in the leg or foot
Coldness in one lower leg or foot compared with the other
Aching or burning at rest, often worse at night

What you See

An ankle and foot with dusky, bluish-purple skin discoloration
Sores or ulcers on the feet or toes that are slow to heal
Shiny skin, or color changes: pale, bluish, or dusky
Hair loss on the legs, feet, or toes
Slower toenail growth or thickened nails

What you Notice

A woman pausing on a park bench mid-walk, holding her knee
Walking shorter distances before the pain sets in
Having to stop or slow down sooner than you used to
Leg pain that eases when you hang your foot off the bed
In men, new difficulty with erections linked to reduced blood flow

Up to 4 in 10 people with PAD don't have the classic leg cramping. That's why people with diabetes or a history of smoking benefit from screening even without obvious symptoms.

What causes PAD

Nearly always, it comes down to plaque slowly narrowing the arteries that feed your legs.

Plaque builds up
01

Plaque builds up

Fatty deposits, cholesterol, and calcium gradually collect along the inner walls of the arteries that carry blood to your legs, a process called atherosclerosis.

Arteries narrow
02

Arteries narrow

As plaque thickens, the channel inside the artery shrinks and stiffens, so less oxygen-rich blood reaches the muscles of the legs and feet.

Muscles starve for oxygen
03

Muscles starve for oxygen

When you walk, the leg muscles demand more blood than the narrowed artery can deliver, which is why they cramp, then ease once you rest.

Who's most at risk

PAD shares its risk factors with heart disease. Smoking and diabetes carry the most weight, but they rarely act alone, and the more that stack up, the higher your risk.

The same habits that lower PAD risk, like staying active and managing blood sugar and cholesterol, also protect your heart.

Smoking

Smoking is the single strongest risk factor. It dramatically accelerates artery narrowing and worsens outcomes.

Diabetes

High blood sugar damages and narrows arteries, making PAD more common, more severe, and harder to feel.

Age over 50

Risk climbs steadily with age as arteries naturally stiffen and plaque accumulates.

High blood pressure & cholesterol

Both speed up plaque buildup throughout the body, including the arteries of the legs.

Family or personal history

A history of PAD, heart disease, or stroke in you or close relatives raises your risk.

Excess weight & inactivity

Extra weight and limited movement compound other risk factors and slow circulation.

Why it shouldn't wait

PAD is treatable, but it progresses

Caught early, PAD is very manageable. Left alone, reduced blood flow can lead to serious problems in the leg and beyond.

Non-healing wounds

Poor blood flow means cuts and sores on the feet heal slowly, raising the risk of infection.

Critical limb ischemia

Severe, advanced PAD with pain even at rest and tissue loss that can threaten the limb if untreated.

Heart attack & stroke

PAD is a red flag for artery disease body-wide, so it sharply raises cardiovascular risk.

Loss of mobility

Worsening leg pain can quietly shrink how far, and how independently, you're able to move.

The good news

With today's minimally invasive treatments, the vast majority of PAD is managed successfully, and treating it protects your heart at the same time.

How we diagnose PAD

It starts simply, with quick, painless tests that tell us exactly how well blood is reaching your legs.

01

Vascular screening

A specialist reviews your symptoms and history, checks pulses in your legs and feet, and looks at the skin.

02

Ankle-Brachial Index (ABI)

A simple, painless test compares blood pressure at your ankle and arm to measure how well blood reaches your legs.

03

Duplex ultrasound

An imaging scan in our accredited vascular lab pinpoints exactly where and how severely an artery is narrowed.

EVVS specialist performing an ankle-brachial index test

How we treat PAD

Care starts with the simplest steps and adds minimally invasive procedures only when they're needed and matched to your arteries.

First-line care

Lifestyle & supervised walking

A structured walking program, quitting smoking, and managing blood sugar and cholesterol can meaningfully improve how far you walk.

Best forEarly & mild PAD
Medical therapy

Medication management

Medicines to manage cholesterol, blood pressure, blood sugar, and clotting risk help slow PAD and protect the heart.

Best forReducing progression & risk
Plaque removal

Atherectomy

A catheter-based procedure that shaves or sands hardened plaque from inside a narrowed leg artery to reopen blood flow.

Best forBlocked or hardened arteries
Learn more
Reopen the artery

Angioplasty & stenting

A tiny balloon widens the narrowed artery, and when needed a small stent holds it open, restoring circulation.

Best forSignificant narrowing
Calcium modification

Intravascular Lithotripsy

Sound-wave energy gently cracks stubborn calcium in the artery wall so the vessel can be safely reopened.

Best forHeavily calcified arteries
Learn more

Every plan is built around your test results and your goals. Your specialist will walk you through exactly what's recommended and why.

Peripheral artery disease, answered

The questions patients ask us most about PAD.

PAD reduces blood flow to the limbs. Left untreated, it can lead to non-healing wounds and, in severe cases, limb loss. Just as important, it's a warning sign that arteries elsewhere may be narrowing too, so people with PAD have a higher risk of heart attack and stroke. The reassuring part is that it's very treatable, especially when caught early.

Insurance

When your veins cause symptoms like aching, swelling, or skin changes, treatment is typically considered medically necessary, including under Medicare. We'll help you verify your benefits.

Most major plans accepted

Inland Empire Health Plan (IEHP)AetnaAnthem Blue CrossMedicareBlue ShieldCigna
Verify your coverage

Locations

Care close to home across the Inland Empire, High Desert, and Coachella Valley. Every office has on-site ultrasound.

Inland Empire

High Desert

Find your nearest office

Don't wait on your circulation.

A vascular screening today can protect your mobility and your heart. Quick, painless, and offered at all 6 of our Southern California offices.

Book a Screening
or call us directly (800) 827-4267