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Stop Masking Your Knee Arthritis Pain. Treat It at the Source.

Cortisone and gel shots can quiet knee arthritis pain for a while, but they don't change what's driving it. GAE (genicular artery embolization) is designed to target what is actually contributing to the pain.

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FDA
FDA-cleared technology
Performed by fellowship-trained specialists
What it treats
The root cause
vs. the symptoms
Typical relief
2+ years for most
vs. weeks to months
Repeat visits
Rarely needed
vs. every few months
Safe to repeat
Joint left intact
vs. limits on steroids

First, what kind of shot?

“Injections” usually means one of two things

Both are common, both are done in the office, and both can help for a time. Knowing which is which makes the comparison with GAE clearer.

Cortisone (steroid)

A steroid injected into the joint to calm inflammation. Relief can come quickly, but it's temporary, often a few weeks to a few months. And repeated steroid injections may have downsides, including concern for cartilage damage over time, which is why doctors limit how often you receive them.

Gel (hyaluronic acid)

Also called viscosupplementation. It adds temporary cushioning to the joint. Some people feel relief for up to six months; for others it does little, and like cortisone, it eventually wears off.

Are you treating the pain, or what is causing the pain?

This is the real difference. One quiets the pain signal for a while; the other goes after what's driving it.

Injections

Temporarily reduce symptoms, imprecisely. Medication is placed into the joint and calms inflammation wherever it settles. When it wears off, the pain often returns.

GAE

Treats the source, precisely. A catheter identifies and treats the specific abnormal blood vessels driving inflammation inside the arthritic knee.

Angiogram before GAE showing abnormal overactive blood vessels supplying the inflamed knee

Before GAE

The angiogram shows abnormal, overactive blood vessels (neovessels) supplying the inflamed areas around the arthritic knee. These vessels can contribute to ongoing inflammation and pain.

Illustration of a small catheter delivering treatment directly into the abnormal vessels

During GAE

A small catheter is guided directly to these abnormal vessels, allowing precise treatment of the blood supply contributing to inflammation.

Angiogram after GAE showing reduced blood flow to the treated vessels

After GAE

The treated vessels show reduced blood flow, helping decrease the inflammatory process associated with knee pain.

GAE is not just treating where the pain is felt, it is targeting the abnormal blood vessels contributing to why the knee hurts.

Relief measured in years, not appointments.

Everyone wants the same thing from a knee treatment: relief that sticks, without living from one visit to the next.

GAE

Years, from one visit. Most patients experience relief lasting two years or longer after GAE, from a single outpatient procedure. Many notice improvement within weeks, with continued gains over the following months.

Injections

Weeks to months, then back again. Cortisone fades in weeks to months and gel may last up to six for some, so shots become a cycle every few months. Many patients find each round wears off a little faster than the last.

A grandfather teaching his grandson to fish by a pondA grandfather teaching his grandson to fish by a pond

Which treatment may be right for you?

An honest look at where each option tends to fit. Your specialist confirms the right path after reviewing your imaging.

GAE may fit if…

Injections have stopped working, or you're tired of coming back every few months
Your knee pain limits daily life and you want lasting relief
You'd rather treat the cause than keep managing the symptoms
You want to delay or avoid a knee replacement

Injections may still make sense if…

Your arthritis is early or mild and flares only now and then
You need short-term relief before a trip, event, or planned procedure
Shots have given you good, lasting results in the past
You'd like to try the simplest in-office option first

FAQ

Everything you need to know

Straight answers on how GAE and injections really compare, from the specialist who performs GAE.

Dr. Pushpinder Sivia
Dr. Pushpinder Sivia
Board-certified · GAE specialist
“
If injections are providing lasting relief, they may be a reasonable option. But when relief becomes shorter, or you find yourself returning for repeated injections, it may be time to look at what is actually driving the pain.

Most patients experience relief lasting two years or longer. Many begin noticing improvement within weeks, with continued improvement over the following months. Unlike injections that often wear off and require repeat visits, GAE is typically performed as a one-time outpatient procedure, with repeat treatment available if needed.

Tired of chasing relief every few months?

Book a knee pain consultation with our GAE specialist. We’ll review your knee, explain how GAE compares with the shots you’ve tried, and help you decide, with no pressure.

Book a Knee Pain Consultation
or call us directly (800) 827-4267