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Lasting knee arthritis relief with GAE. Skip the knee replacement.

When injections or physical therapy stop helping, there's still a next step. Genicular Artery Embolization (GAE) is a same-day, nonsurgical procedure that blocks the abnormal blood vessels driving arthritis inflammation — relief at the source, without surgery or a long recovery.

4 in 5

Patients report lasting relief

Meaningful, lasting improvement after GAE

800+

GAE procedures performed

Real experience with this exact procedure, close to home

~30 min

Average procedure time

Through a pinhole in the skin; no incision, no stitches

As seen on
As featured on ABC As featured on NBC As featured on CBS As featured on FOX As featured on KTLA 5 As featured on Palm Springs Life
Grandmother laughing as she hugs her grandchild in the backyard

Your knee pain has a source, and GAE treats it.

If knee arthritis has you avoiding the stairs, the garden, or your morning walk, there’s a newer option worth knowing about. GAE quiets arthritis pain right at its source, using FDA-cleared technology and no surgery. Empire Vein is the leading GAE provider in the Coachella Valley and Inland Empire.

G

Genicular

Genicular arteries are the cluster of small arteries that wrap around and supply blood to your knee joint.

A

Artery

In osteoarthritis, these vessels overgrow and inflame the lining of the joint. That inflammation is a major driver of pain.

E

Embolization

We gently reduce that abnormal blood flow, calming inflammation right at its source.

Procedure time

~30 min

Start to finish, outpatient

Incision & anesthesia

Local only

Awake, just a pinhole, no cutting

Recovery

Same day

Home that day; light activity in 1–2 days

Relief

2+ years

Eases over weeks, lasting & repeatable

Proven & safe

The #1 fastest-growing alternative to knee replacement.

Most patients haven't heard of GAE yet, but the research runs deep. More than a dozen clinical studies back it up, including randomized controlled trials. Our own team has performed hundreds of these procedures right here in Southern California.

A man sitting outdoors holding his aching knee

12+

Clinical studies, including randomized controlled trials

Nothing cut

Your natural knee is preserved, not replaced

Next day

Back to daily activities, with minimal downtime

What’s really happening inside your knee

Knee arthritis isn’t only about worn cartilage. There’s a vascular side most people never hear about, and seeing it makes clear why GAE works differently than pills or injections.

Healthy knee
Arthritic knee
Blood supply
A normal, stable network of arteries feeds the joint lining
Extra, leaky vessels overgrow around the joint lining
Inflammation
None, no abnormal vessel growth or swelling
Ongoing swelling that fuels the pain cycle
Pain nerves
Quiet, the joint moves comfortably
Over-stimulated, chronic, aching pain
Knee angiogram before GAE, A dense tangle of abnormal vessels feeding the joint
Pain source
Before

A dense tangle of abnormal vessels feeding the joint

Knee angiogram after GAE, That excess blood flow reduced, and the pain with it
Calmer, treated
After

That excess blood flow reduced, and the pain with it

See inside a real patient’s knee

These are actual angiograms from a real Empire Vein & Vascular patient, not an illustration. On the left, a dense tangle of overgrown vessels crowds the knee. This is the blood supply feeding the inflammation and pain you just read about.

On the right, after GAE, that excess flow is calmed. Less inflammation means less pain, and your knee itself was never touched.

The key difference: GAE treats the abnormal blood vessels fueling knee pain. Your normal cartilage is left completely intact.

Individual results vary.

An alternative to knee replacement

If you’ve been told surgery is your only option, here’s what makes GAE different.

Preserves your cartilage

A knee replacement cuts away bone and cartilage for an artificial joint. GAE removes nothing. Your own knee stays whole, which keeps your future options open.

Relief begins within days

There’s no overnight switch, and that’s normal. GAE calms the abnormal blood flow feeding your arthritis, so the inflammation settles. Most patients feel their knee pain begin to ease within days and keep improving over the weeks that follow.

Years of lasting relief

GAE targets the root cause, not just the symptom. In studies, most patients report significant relief lasting two years or longer. That’s years, not the weeks you’d get from a typical injection. And because nothing is removed or fused, it’s repeatable when needed.

Your procedure, start to finish

Three steps, one outpatient visit, about 30 minutes start to finish, and home the same day.

A tiny pinhole
01

A tiny pinhole

Your physician numbs a small area of your upper thigh, then guides a thin, flexible catheter into the artery through a puncture no bigger than a pinhole. No incision, no stitches.

Find the source
02

Find the source

Using live X-ray imaging, your physician steers the catheter to the small genicular arteries around your knee. These are the overactive vessels feeding the inflammation.

Calm the inflammation
03

Calm the inflammation

Through the catheter, your physician releases Embosphere® Microspheres. These tiny gel spheres slow the excess blood flow driving the inflammation, affecting only the overactive vessels. Your knee’s normal circulation keeps working. Most people feel pain easing over the following few weeks.

Embosphere Microspheres

Embosphere® Microspheres

GAE works using Embosphere® Microspheres: soft gel spheres. Released through the catheter, they settle into the abnormal arteries feeding your knee's inflammation and gently shut them down. Your normal arteries stay intact. Doctors have trusted these same microspheres for decades to treat uterine fibroids, tumors, and internal bleeding.

2-minute self-check

Could GAE help your knee?

Answer five quick questions about your knee pain, and we’ll tell you whether this nonsurgical option could be a fit. It’s not a diagnosis, just a guided first step.

Check my knee symptoms

5 QUESTIONS · UNDER 2 MINUTES · NO SIGN-UPS

How does GAE compare?

See how GAE compares to injections and knee replacement on relief, recovery, and risk.

GAE
GAE
Injections
Injections
Knee Replacement
Knee Replacement
Minimally invasive
Long-term pain relief
Preserves knee cartilage
Recovery time
Days
Days
Months
Requires hospital stay
Risk of major complications
Low
Low
Higher
Good option if avoiding surgery

Is GAE right for you?

GAE isn’t for everyone, but for the right candidate, it can mean lasting relief without surgery. Here’s who tends to benefit, and what they often feel afterward.

You may be a good fit if…

You have moderate to severe knee osteoarthritis
You’re not ready for, or want to avoid, knee replacement surgery
Pain continues despite injections, medication, or physical therapy
You want a minimally invasive option with a faster recovery

What patients often notice after

Reduced knee pain during everyday activities
Greater ease walking, climbing stairs, and staying active
Improved mobility and flexibility
Little to no downtime, with a fast return to your routine
A chance to delay or avoid future knee surgery
Dr. Pushpinder Sivia

Dr. Pushpinder Sivia

President, Empire Vein & Vascular Specialists

In our surgeon’s words

Meet the specialist behind your GAE

“For the right patient, GAE can mean years of relief without ever stepping into an operating room. Helping people get back to the things they’d given up on, that’s the part of this work I love most.”

Board-Certified Vascular Surgeon More than 800 GAE procedures performed Top Physician, Palm Springs Life, 2025 and 2026
Read Dr. Sivia’s full profile
Cover of “Skip the Scalpel,” the free Empire Vein patient e-book on genicular artery embolization for knee arthritis

Free patient guide

Skip the Scalpel

Our plain-language guide to easing knee arthritis pain without surgery: what GAE is, who makes a good candidate, what recovery really looks like, and the questions worth asking your doctor.

Download the guide

Still have questions?

GAE stands for Genicular Artery Embolization. It’s a minimally invasive, outpatient procedure that relieves knee osteoarthritis pain by reducing the abnormal blood flow that fuels inflammation in the joint. No surgery, no implant, no hospital stay.

Get back on your feet, without surgery.

Find out if GAE is right for your knee pain in a single consultation.

Book a Consultation
or call us directly (800) 827-4267